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Janet Lau's thesis describes her studies into the use of phthalocyanine-based photosensitizers in combined chemo- and photodynamic therapy (PDT) and targeted PDT. In order to carry out this study, Lau uses several approaches: conjugation with a chemotherapeutic oxaliplatin derivative, use of a polyamine ligand 2 with a view to targeting the polyamine transporters over-expressed in tumor cells, and employment of a quencher that can inhibit their photodynamic activity but can still be removed under a tumor-associated environment such as low pH and high thiol concentration. This thesis reports dual activatable photosensitizers for the first time. Overall the studies included are original and the effects have been well demonstrated at the cellular level. The work in this thesis is of much current interest and importance, and can pave foundation for further developments. Accordingly, parts of the results have been published in prestigious scientific journals.

Chemistry --- Physical Sciences & Mathematics --- Physical & Theoretical Chemistry --- Photochemotherapy. --- Cancer --- Chemotherapy. --- Photodynamic therapy --- Chemistry. --- Cancer research. --- Physical chemistry. --- Medicinal chemistry. --- Physical Chemistry. --- Medicinal Chemistry. --- Cancer Research. --- Antineoplastic agents --- Chemotherapy --- Photosensitization, Biological --- Phototherapy --- Treatment --- Chemistry, Physical organic. --- Biochemistry. --- Oncology. --- Tumors --- Biological chemistry --- Chemical composition of organisms --- Organisms --- Physiological chemistry --- Biology --- Medical sciences --- Chemistry, Physical organic --- Chemistry, Organic --- Chemistry, Physical and theoretical --- Composition --- Chemistry, Theoretical --- Physical chemistry --- Theoretical chemistry --- Cancer research --- Chemistry, Medical and pharmaceutical --- Chemistry, Pharmaceutical --- Drug chemistry --- Drugs --- Medical chemistry --- Medicinal chemistry --- Pharmacochemistry --- Photosensitizing compounds.

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Over 1000 references to monographic and serial publications. Intended to inform the reader as to the scope and depth of the stress burnout syndrome. Alphabetical arrangement by authors. Each entry gives bibliographical information and lengthy annotations. Contains lists of signs and symptoms, courses and sources, and coping strategies.

Burn out (Psychology) --- Burnout, Professional --- Stress, Psychological --- Behavioral Symptoms --- Psychophysiology --- Psychological Phenomena and Processes --- Behavior --- Psychiatry and Psychology --- Behavior and Behavior Mechanisms --- Social Sciences --- Psychology --- Behavioral Symptom --- Symptom, Behavioral --- Symptoms, Behavioral --- Burnout (Psychology) --- Job satisfaction --- Job stress --- Motivation (Psychology) --- Stress (Psychology) --- Psychological Stress --- Stress, Psychologic --- Stressor, Psychological --- Life Stress --- Life Stresses --- Psychologic Stress --- Psychological Stresses --- Psychological Stressor --- Psychological Stressors --- Stress, Life --- Stresses, Life --- Stresses, Psychological --- Stressors, Psychological --- Career Burnout --- Occupational Burnout --- Burnout, Career --- Burnout, Occupational --- Professional Burnout --- Compassion Fatigue --- Behavior And Behavior Mechanism --- Acceptance Process --- Acceptance Processes --- Behaviors --- Process, Acceptance --- Processes, Acceptance --- Psychologic Processes --- Psychologic Processes and Principles --- Psychological Processes --- Phenomena, Psychological --- Processes, Psychologic --- Processes, Psychological --- Psychological Phenomenas --- Psychological Processe --- Mind-Body Relationship (Physiology) --- Physiologic Psychology --- Physiological Psychology --- Psychology, Physiologic --- Mind-Body Relations (Physiology) --- Psychology, Physiological --- Mind Body Relations (Physiology) --- Mind Body Relationship (Physiology) --- Mind-Body Relation (Physiology) --- Mind-Body Relationships (Physiology) --- Physiologic Psychologies --- Psychologies, Physiologic --- Relation, Mind-Body (Physiology) --- Relations, Mind-Body (Physiology) --- Relationship, Mind-Body (Physiology) --- Relationships, Mind-Body (Physiology) --- Psychosomatic Medicine --- Mind-Body Relations, Metaphysical --- Abstracts. --- Abstracts --- Psychological Phenomena --- Psychiatry

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Menominee Indians --- Indian cooking. --- Algonquian Indians --- Indians of North America --- Cookery, Indian --- Indian cookery --- Cooking --- Food. --- Social life and customs. --- Weso, T. F. Pecore --- Weso, Thomas --- Westo, Thomas Pecore --- Menominee Indian Reservation (Wis.) --- Menominee Reservation (Wis.) --- Menomonee Indian Reservation (Wis.) --- Menomonee Reservation (Wis.) --- Weso, Thomas Pecore

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This book is aimed at senior undergraduates, graduates and engineers. It fills the gap between the numerous textbooks on traditional Applied Mechanics and postgraduate books on Finite Element Methods.Fills the gap between the applied mechanics and finite element methodsDiscusses basic structural concepts and energy theorems, the discrete system, in-plane quadrilateral elements, field problems and mathematical modelling, among other topicsAimed at senior undergraduates, graduates and engineers

Engineering sciences. Technology --- Finite element method. --- Engineering mathematics.

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This text is the primary recommendation of the UK Engineering Council Faculty of Technology to all British universities as of approved standard and quality for use as a text for the Board's own examinations. It introduces the fundamental concepts and principles of statics and stress analysis as the essential reading for first year engineering students. Worked examples from the authors experience reinforce comprehension of key concepts. Tutorial solutions with explanation in extended detail have been provided for students. Key elements include: use of free-body diagrams to help problem solving;

Structural analysis (Engineering)